NLRP3_HUMAN - 1036 amino acids
Alzheimer
NC
CN
Seq1 = 1 Seq2 = 9 Seq3 = 13 Seq4 = 16 Seq5 = 11 Seq6 = 29 Seq7 = 29 Seq8 = 31 Seq9 = 20 Seq10 = 14 Seq11 = 9 Seq12 = 10 Seq13 = 15 Seq14 = 17 Seq15 = 12 Seq16 = 9 Seq17 = 10 Seq18 = 13 Seq19 = 15 Seq20 = 10 Seq21 = 23 Seq22 = 18 Seq23 = 19 Seq24 = 24 Seq25 = 14 Seq26 = 15 Seq27 = 5 Seq28 = 13 Seq29 = 15 Seq30 = 21 Seq31 = 9 Seq32 = 5 Seq33 = 2 Seq34 = 11 Seq35 = 8 Seq36 = 11 Seq37 = 7 Seq38 = 7 Seq39 = 11 Seq40 = 21 Seq41 = 15 Seq42 = 32 Seq43 = 25 Seq44 = 19 Seq45 = 14 Seq46 = 12 Seq47 = 10 Seq48 = 9 Seq49 = 19 Seq50 = 16 Seq51 = 18 Seq52 = 22 Seq53 = 8 Seq54 = 10 Seq55 = 19 Seq56 = 24 Seq57 = 41 Seq58 = 24 Seq59 = 19 Seq60 = 14 Seq61 = 6 Seq62 = 12 Seq63 = 27 Seq64 = 31 Seq65 = 24 Seq66 = 14 Seq67 = 7 Seq68 = 9 Seq69 = 7 Seq70 = 9 Seq71 = 10 Seq72 = 21 Seq73 = 20 Seq74 = 17 Seq75 = 13 Seq76 = 14 Seq77 = 16 Seq78 = 8 Seq79 = 7 Seq80 = 4 Seq81 = 13 Seq82 = 11 Seq83 = 12 Seq84 = 24 Seq85 = 10 Seq86 = 5 Seq87 = 2 Seq88 = 8 Seq89 = 8 Seq90 = 9 Seq91 = 16 Seq92 = 22 Seq93 = 34 Seq94 = 26 Seq95 = 20 Seq96 = 18 Seq97 = 9 Seq98 = 13 Seq99 = 13 Seq100 = 6 Seq101 = 6 Seq102 = 10 Seq103 = 20 Seq104 = 15 Seq105 = 13 Seq106 = 5 Seq107 = 13 Seq108 = 11 Seq109 = 13 Seq110 = 26 Seq111 = 14 Seq112 = 12 Seq113 = 19 Seq114 = 18 Seq115 = 14 Seq116 = 10 Seq117 = 12 Seq118 = 5 Seq119 = 15 Seq120 = 12 Seq121 = 12 Seq122 = 13 Seq123 = 11 Seq124 = 6 Seq125 = 16 Seq126 = 10 Seq127 = 19 Seq128 = 6 Seq129 = 12 Seq130 = 15 Seq131 = 9 Seq132 = 8 Seq133 = 12 Seq134 = 20 Seq135 = 20 Seq136 = 12 Seq137 = 14 Seq138 = 17 Seq139 = 18 Seq140 = 14 Seq141 = 15 Seq142 = 20 Seq143 = 17 Seq144 = 24 Seq145 = 15 Seq146 = 21 Seq147 = 3 Seq148 = 9 Seq149 = 10 Seq150 = 10 Seq151 = 15 Seq152 = 23 Seq153 = 29 Seq154 = 30 Seq155 = 23 Seq156 = 27 Seq157 = 23 Seq158 = 14 Seq159 = 6 Seq160 = 11 Seq161 = 5 Seq162 = 10 Seq163 = 13 Seq164 = 19 Seq165 = 28 Seq166 = 28 Seq167 = 21 Seq168 = 21 Seq169 = 25 Seq170 = 10 Seq171 = 9 Seq172 = 9 Seq173 = 8 Seq174 = 13 Seq175 = 15 Seq176 = 17 Seq177 = 21 Seq178 = 10 Seq179 = 19 Seq180 = 14 Seq181 = 12 Seq182 = 7 Seq183 = 13 Seq184 = 10 Seq185 = 12 Seq186 = 18 Seq187 = 27 Seq188 = 29 Seq189 = 28 Seq190 = 22 Seq191 = 24 Seq192 = 16 Seq193 = 7 Seq194 = 6 Seq195 = 8 Seq196 = 10 Seq197 = 17 Seq198 = 18 Seq199 = 12 Seq200 = 11 Seq201 = 17 Seq202 = 13 Seq203 = 8 Seq204 = 6 Seq205 = 16 Seq206 = 21 SeqR2 = 7 SeqR3 = 12 SeqR4 = 13 SeqR5 = 10 SeqR6 = 27 SeqR7 = 32 SeqR8 = 26 SeqR9 = 21 SeqR10 = 7 SeqR11 = 8 SeqR12 = 17 SeqR13 = 17 SeqR14 = 15 SeqR15 = 14 SeqR16 = 16 SeqR17 = 11 SeqR18 = 9 SeqR19 = 17 SeqR20 = 8 SeqR21 = 21 SeqR22 = 17 SeqR23 = 18 SeqR24 = 15 SeqR25 = 12 SeqR26 = 13 SeqR27 = 11 SeqR28 = 11 SeqR29 = 13 SeqR30 = 20 SeqR31 = 13 SeqR32 = 16 SeqR33 = 2 SeqR34 = 4 SeqR35 = 11 SeqR36 = 6 SeqR37 = 11 SeqR38 = 6 SeqR39 = 8 SeqR40 = 21 SeqR41 = 13 SeqR42 = 36 SeqR43 = 29 SeqR44 = 25 SeqR45 = 9 SeqR46 = 10 SeqR47 = 5 SeqR48 = 7 SeqR49 = 8 SeqR50 = 19 SeqR51 = 19 SeqR52 = 15 SeqR53 = 8 SeqR54 = 10 SeqR55 = 16 SeqR56 = 34 SeqR57 = 44 SeqR58 = 25 SeqR59 = 24 SeqR60 = 10 SeqR61 = 19 SeqR62 = 13 SeqR63 = 30 SeqR64 = 33 SeqR65 = 24 SeqR66 = 9 SeqR67 = 6 SeqR68 = 13 SeqR69 = 10 SeqR70 = 11 SeqR71 = 13 SeqR72 = 24 SeqR73 = 23 SeqR74 = 14 SeqR75 = 11 SeqR76 = 7 SeqR77 = 15 SeqR78 = 7 SeqR79 = 5 SeqR80 = 4 SeqR81 = 7 SeqR82 = 18 SeqR83 = 24 SeqR84 = 23 SeqR85 = 9 SeqR86 = 9 SeqR87 = 3 SeqR88 = 3 SeqR89 = 2 SeqR90 = 7 SeqR91 = 13 SeqR92 = 21 SeqR93 = 21 SeqR94 = 20 SeqR95 = 19 SeqR96 = 20 SeqR97 = 16 SeqR98 = 17 SeqR99 = 14 SeqR100 = 3 SeqR101 = 6 SeqR102 = 10 SeqR103 = 12 SeqR104 = 11 SeqR105 = 11 SeqR106 = 8 SeqR107 = 8 SeqR108 = 13 SeqR109 = 24 SeqR110 = 21 SeqR111 = 16 SeqR112 = 12 SeqR113 = 17 SeqR114 = 23 SeqR115 = 15 SeqR116 = 11 SeqR117 = 10 SeqR118 = 5 SeqR119 = 18 SeqR120 = 16 SeqR121 = 10 SeqR122 = 14 SeqR123 = 12 SeqR124 = 4 SeqR125 = 13 SeqR126 = 8 SeqR127 = 11 SeqR128 = 6 SeqR129 = 12 SeqR130 = 17 SeqR131 = 7 SeqR132 = 9 SeqR133 = 12 SeqR134 = 18 SeqR135 = 16 SeqR136 = 8 SeqR137 = 19 SeqR138 = 24 SeqR139 = 16 SeqR140 = 18 SeqR141 = 20 SeqR142 = 20 SeqR143 = 15 SeqR144 = 26 SeqR145 = 10 SeqR146 = 16 SeqR147 = 11 SeqR148 = 4 SeqR149 = 9 SeqR150 = 7 SeqR151 = 13 SeqR152 = 13 SeqR153 = 31 SeqR154 = 21 SeqR155 = 23 SeqR156 = 27 SeqR157 = 27 SeqR158 = 14 SeqR159 = 4 SeqR160 = 9 SeqR161 = 12 SeqR162 = 10 SeqR163 = 12 SeqR164 = 24 SeqR165 = 16 SeqR166 = 26 SeqR167 = 27 SeqR168 = 22 SeqR169 = 16 SeqR170 = 9 SeqR171 = 10 SeqR172 = 10 SeqR173 = 9 SeqR174 = 9 SeqR175 = 13 SeqR176 = 16 SeqR177 = 15 SeqR178 = 8 SeqR179 = 16 SeqR180 = 13 SeqR181 = 4 SeqR182 = 5 SeqR183 = 10 SeqR184 = 14 SeqR185 = 8 SeqR186 = 22 SeqR187 = 30 SeqR188 = 28 SeqR189 = 17 SeqR190 = 13 SeqR191 = 19 SeqR192 = 15 SeqR193 = 6 SeqR194 = 4 SeqR195 = 5 SeqR196 = 9 SeqR197 = 9 SeqR198 = 12 SeqR199 = 12 SeqR200 = 14 SeqR201 = 8 SeqR202 = 6 SeqR203 = 3 SeqR204 = 8 SeqR205 = 13 SeqR206 = 18
1 MKMASTRCKL 1
2 TRCKLARYLE 9
3 ARYLEDLEDV 13
4 DLEDVDLKKF 16
5 DLKKFKMHLE 11
6 KMHLEDYPPQ 29
7 DYPPQKGCIP 29
8 KGCIPLPRGQ 31
9 LPRGQTEKAD 20
10 TEKADHVDLA 14
11 HVDLATLMID 9
12 TLMIDFNGEE 10
13 FNGEEKAWAM 15
14 KAWAMAVWIF 17
15 AVWIFAAINR 12
16 AAINRRDLYE 9
17 RDLYEKAKRD 10
18 KAKRDEPKWG 13
19 EPKWGSDNAR 15
20 SDNARVSNPT 10
21 VSNPTVICQE 23
22 VICQEDSIEE 18
23 DSIEEEWMGL 19
24 EWMGLLEYLS 24
25 LEYLSRISIC 14
26 RISICKMKKD 15
27 KMKKDYRKKY 5
28 YRKKYRKYVR 13
29 RKYVRSRFQC 15
30 SRFQCIEDRN 21
31 IEDRNARLGE 9
32 ARLGESVSLN 5
33 SVSLNKRYTR 2
34 KRYTRLRLIK 11
35 LRLIKEHRSQ 8
36 EHRSQQEREQ 11
37 QEREQELLAI 7
38 ELLAIGKTKT 7
39 GKTKTCESPV 11
40 CESPVSPIKM 21
41 SPIKMELLFD 15
42 ELLFDPDDEH 32
43 PDDEHSEPVH 25
44 SEPVHTVVFQ 19
45 TVVFQGAAGI 14
46 GAAGIGKTIL 12
47 GKTILARKMM 10
48 ARKMMLDWAS 9
49 LDWASGTLYQ 19
50 GTLYQDRFDY 16
51 DRFDYLFYIH 18
52 LFYIHCREVS 22
53 CREVSLVTQR 8
54 LVTQRSLGDL 10
55 SLGDLIMSCC 19
56 IMSCCPDPNP 24
57 PDPNPPIHKI 41
58 PIHKIVRKPS 24
59 VRKPSRILFL 19
60 RILFLMDGFD 14
61 MDGFDELQGA 6
62 ELQGAFDEHI 12
63 FDEHIGPLCT 27
64 GPLCTDWQKA 31
65 DWQKAERGDI 24
66 ERGDILLSSL 14
67 LLSSLIRKKL 7
68 IRKKLLPEAS 9
69 LPEASLLITT 7
70 LLITTRPVAL 9
71 RPVALEKLQH 10
72 EKLQHLLDHP 21
73 LLDHPRHVEI 20
74 RHVEILGFSE 17
75 LGFSEAKRKE 13
76 AKRKEYFFKY 14
77 YFFKYFSDEA 16
78 FSDEAQARAA 8
79 QARAAFSLIQ 7
80 FSLIQENEVL 4
81 ENEVLFTMCF 13
82 FTMCFIPLVC 11
83 IPLVCWIVCT 12
84 WIVCTGLKQQ 24
85 GLKQQMESGK 10
86 MESGKSLAQT 5
87 SLAQTSKTTT 2
88 SKTTTAVYVF 8
89 AVYVFFLSSL 8
90 FLSSLLQPRG 9
91 LQPRGGSQEH 16
92 GSQEHGLCAH 22
93 GLCAHLWGLC 34
94 LWGLCSLAAD 26
95 SLAADGIWNQ 20
96 GIWNQKILFE 18
97 KILFEESDLR 9
98 ESDLRNHGLQ 13
99 NHGLQKADVS 13
100 KADVSAFLRM 6
101 AFLRMNLFQK 6
102 NLFQKEVDCE 10
103 EVDCEKFYSF 20
104 KFYSFIHMTF 15
105 IHMTFQEFFA 13
106 QEFFAAMYYL 5
107 AMYYLLEEEK 13
108 LEEEKEGRTN 11
109 EGRTNVPGSR 13
110 VPGSRLKLPS 26
111 LKLPSRDVTV 14
112 RDVTVLLENY 12
113 LLENYGKFEK 19
114 GKFEKGYLIF 18
115 GYLIFVVRFL 14
116 VVRFLFGLVN 10
117 FGLVNQERTS 12
118 QERTSYLEKK 5
119 YLEKKLSCKI 15
120 LSCKISQQIR 12
121 SQQIRLELLK 12
122 LELLKWIEVK 13
123 WIEVKAKAKK 11
124 AKAKKLQIQP 6
125 LQIQPSQLEL 16
126 SQLELFYCLY 10
127 FYCLYEMQEE 19
128 EMQEEDFVQR 6
129 DFVQRAMDYF 12
130 AMDYFPKIEI 15
131 PKIEINLSTR 9
132 NLSTRMDHMV 8
133 MDHMVSSFCI 12
134 SSFCIENCHR 20
135 ENCHRVESLS 20
136 VESLSLGFLH 12
137 LGFLHNMPKE 14
138 NMPKEEEEEE 17
139 EEEEEKEGRH 18
140 KEGRHLDMVQ 14
141 LDMVQCVLPS 15
142 CVLPSSSHAA 20
143 SSHAACSHGL 17
144 CSHGLVNSHL 24
145 VNSHLTSSFC 15
146 TSSFCRGLFS 21
147 RGLFSVLSTS 3
148 VLSTSQSLTE 9
149 QSLTELDLSD 10
150 LDLSDNSLGD 10
151 NSLGDPGMRV 15
152 PGMRVLCETL 23
153 LCETLQHPGC 29
154 QHPGCNIRRL 30
155 NIRRLWLGRC 23
156 WLGRCGLSHE 27
157 GLSHECCFDI 23
158 CCFDISLVLS 14
159 SLVLSSNQKL 6
160 SNQKLVELDL 11
161 VELDLSDNAL 5
162 SDNALGDFGI 10
163 GDFGIRLLCV 13
164 RLLCVGLKHL 19
165 GLKHLLCNLK 28
166 LCNLKKLWLV 28
167 KLWLVSCCLT 21
168 SCCLTSACCQ 21
169 SACCQDLASV 25
170 DLASVLSTSH 10
171 LSTSHSLTRL 9
172 SLTRLYVGEN 9
173 YVGENALGDS 8
174 ALGDSGVAIL 13
175 GVAILCEKAK 15
176 CEKAKNPQCN 17
177 NPQCNLQKLG 21
178 LQKLGLVNSG 10
179 LVNSGLTSVC 19
180 LTSVCCSALS 14
181 CSALSSVLST 12
182 SVLSTNQNLT 7
183 NQNLTHLYLR 13
184 HLYLRGNTLG 10
185 GNTLGDKGIK 12
186 DKGIKLLCEG 18
187 LLCEGLLHPD 27
188 LLHPDCKLQV 29
189 CKLQVLELDN 28
190 LELDNCNLTS 22
191 CNLTSHCCWD 24
192 HCCWDLSTLL 16
193 LSTLLTSSQS 7
194 TSSQSLRKLS 6
195 LRKLSLGNND 8
196 LGNNDLGDLG 10
197 LGDLGVMMFC 17
198 VMMFCEVLKQ 18
199 EVLKQQSCLL 12
200 QSCLLQNLGL 11
201 QNLGLSEMYF 17
202 SEMYFNYETK 13
203 NYETKSALET 8
204 SALETLQEEK 6
205 LQEEKPELTV 16
206 PELTVVFEPSW 21










1 LKCRTSAMKM 0
2 ELYRALKCRT 7
3 VDELDELYRA 12
4 FKKLDVDELD 13
5 ELHMKFKKLD 10
6 QPPYDELHMK 27
7 PICGKQPPYD 32
8 QGRPLPICGK 26
9 DAKETQGRPL 21
10 ALDVHDAKET 7
11 DIMLTALDVH 8
12 EEGNFDIMLT 17
13 MAWAKEEGNF 17
14 FIWVAMAWAK 15
15 RNIAAFIWVA 14
16 EYLDRRNIAA 16
17 DRKAKEYLDR 11
18 GWKPEDRKAK 9
19 RANDSGWKPE 17
20 TPNSVRANDS 8
21 EQCIVTPNSV 21
22 EEISDEQCIV 17
23 LGMWEEEISD 18
24 SLYELLGMWE 15
25 CISIRSLYEL 12
26 DKKMKCISIR 13
27 YKKRYDKKMK 11
28 RVYKRYKKRY 11
29 CQFRSRVYKR 13
30 NRDEICQFRS 20
31 EGLRANRDEI 13
32 NLSVSEGLRA 16
33 RTYRKNLSVS 2
34 KILRLRTYRK 4
35 QSRHEKILRL 11
36 QEREQQSRHE 6
37 IALLEQEREQ 11
38 TKTKGIALLE 6
39 VPSECTKTKG 8
40 MKIPSVPSEC 21
41 DFLLEMKIPS 13
42 HEDDPDFLLE 36
43 HVPESHEDDP 29
44 QFVVTHVPES 25
45 IGAAGQFVVT 9
46 LITKGIGAAG 10
47 MMKRALITKG 5
48 SAWDLMMKRA 7
49 QYLTGSAWDL 8
50 YDFRDQYLTG 19
51 HIYFLYDFRD 19
52 SVERCHIYFL 15
53 RQTVLSVERC 8
54 LDGLSRQTVL 10
55 CCSMILDGLS 16
56 PNPDPCCSMI 34
57 IKHIPPNPDP 44
58 SPKRVIKHIP 25
59 LFLIRSPKRV 24
60 DFGDMLFLIR 10
61 AGQLEDFGDM 19
62 IHEDFAGQLE 13
63 TCLPGIHEDF 30
64 AKQWDTCLPG 33
65 IDGREAKQWD 24
66 LSSLLIDGRE 9
67 LKKRILSSLL 6
68 SAEPLLKKRI 13
69 TTILLSAEPL 10
70 LAVPRTTILL 11
71 HQLKELAVPR 13
72 PHDLLHQLKE 24
73 IEVHRPHDLL 23
74 ESFGLIEVHR 14
75 EKRKAESFGL 11
76 YKFFYEKRKA 7
77 AEDSFYKFFY 15
78 AARAQAEDSF 7
79 QILSFAARAQ 5
80 LVENEQILSF 4
81 FCMTFLVENE 7
82 CVLPIFCMTF 18
83 TCVIWCVLPI 24
84 QQKLGTCVIW 23
85 KGSEMQQKLG 9
86 TQALSKGSEM 9
87 TTTKSTQALS 3
88 FVYVATTTKS 3
89 LSSLFFVYVA 2
90 GRPQLLSSLF 7
91 HEQSGGRPQL 13
92 HACLGHEQSG 21
93 CLGWLHACLG 21
94 DAALSCLGWL 20
95 QNWIGDAALS 19
96 EFLIKQNWIG 20
97 RLDSEEFLIK 16
98 QLGHNRLDSE 17
99 SVDAKQLGHN 14
100 MRLFASVDAK 3
101 KQFLNMRLFA 6
102 ECDVEKQFLN 10
103 FSYFKECDVE 12
104 FTMHIFSYFK 11
105 AFFEQFTMHI 11
106 LYYMAAFFEQ 8
107 KEEELLYYMA 8
108 NTRGEKEEEL 13
109 RSGPVNTRGE 24
110 SPLKLRSGPV 21
111 VTVDRSPLKL 16
112 YNELLVTVDR 12
113 KEFKGYNELL 17
114 FILYGKEFKG 23
115 LFRVVFILYG 15
116 NVLGFLFRVV 11
117 STREQNVLGF 10
118 KKELYSTREQ 5
119 IKCSLKKELY 18
120 RIQQSIKCSL 16
121 KLLELRIQQS 10
122 KVEIWKLLEL 14
123 KKAKAKVEIW 12
124 PQIQLKKAKA 4
125 LELQSPQIQL 13
126 YLCYFLELQS 8
127 EEQMEYLCYF 11
128 RQVFDEEQME 6
129 FYDMARQVFD 12
130 IEIKPFYDMA 17
131 RTSLNIEIKP 7
132 VMHDMRTSLN 9
133 ICFSSVMHDM 12
134 RHCNEICFSS 18
135 SLSEVRHCNE 16
136 HLFGLSLSEV 8
137 EKPMNHLFGL 19
138 EEEEEEKPMN 24
139 HRGEKEEEEE 16
140 QVMDLHRGEK 18
141 SPLVCQVMDL 20
142 AAHSSSPLVC 20
143 LGHSCAAHSS 15
144 LHSNVLGHSC 26
145 CFSSTLHSNV 10
146 SFLGRCFSST 16
147 STSLVSFLGR 11
148 ETLSQSTSLV 4
149 DSLDLETLSQ 9
150 DGLSNDSLDL 7
151 VRMGPDGLSN 13
152 LTECLVRMGP 13
153 CGPHQLTECL 31
154 LRRINCGPHQ 21
155 CRGLWLRRIN 23
156 EHSLGCRGLW 27
157 IDFCCEHSLG 27
158 SLVLSIDFCC 14
159 LKQNSSLVLS 4
160 LDLEVLKQNS 9
161 LANDSLDLEV 12
162 IGFDGLANDS 10
163 VCLLRIGFDG 12
164 LHKLGVCLLR 24
165 KLNCLLHKLG 16
166 VLWLKKLNCL 26
167 TLCCSVLWLK 27
168 QCCASTLCCS 22
169 VSALDQCCAS 16
170 HSTSLVSALD 9
171 LRTLSHSTSL 10
172 NEGVYLRTLS 10
173 SDGLANEGVY 9
174 LIAVGSDGLA 9
175 KAKECLIAVG 13
176 NCQPNKAKEC 16
177 GLKQLNCQPN 15
178 GSNVLGLKQL 8
179 CVSTLGSNVL 16
180 SLASCCVSTL 13
181 TSLVSSLASC 4
182 TLNQNTSLVS 5
183 RLYLHTLNQN 10
184 GLTNGRLYLH 14
185 KIGKDGLTNG 8
186 GECLLKIGKD 22
187 DPHLLGECLL 30
188 VQLKCDPHLL 28
189 NDLELVQLKC 17
190 STLNCNDLEL 13
191 DWCCHSTLNC 19
192 LLTSLDWCCH 15
193 SQSSTLLTSL 6
194 SLKRLSQSST 4
195 DNNGLSLKRL 5
196 GLDGLDNNGL 9
197 CFMMVGLDGL 9
198 QKLVECFMMV 12
199 LLCSQQKLVE 12
200 LGLNQLLCSQ 14
201 FYMESLGLNQ 8
202 KTEYNFYMES 6
203 TELASKTEYN 3
204 KEEQLTELAS 8
205 VTLEPKEEQL 13
206 WSPEFVVTLEP 18