Disease Motifs
Investigating the Biomechanics of Disease
Go back to the Home page Resources About this site Biological Research Services Contact this Site

Cancer

There are 41 Cancer proteins within the PD set

AIMP2_HUMAN; AT132_HUMAN; ATX2_HUMAN; AUXI_HUMAN; CDK5_HUMAN; DCTN1_HUMAN; DDIT4_HUMAN; DPOG2_HUMAN; FGF20_HUMAN; FXRD1_HUMAN; IF4G1_HUMAN; KLK6_HUMAN; LRRK2_HUMAN; MIMIT_HUMAN; NDUA1_HUMAN; NDUF4_HUMAN; PARK7_HUMAN; PAWR_HUMAN; PDE8B_HUMAN; PERQ2_HUMAN; PGFRB_HUMAN; PIEZ1_HUMAN; PINK1_HUMAN; PRKN2_HUMAN; PRKRA_HUMAN; PSN1_HUMAN; RNF11_HUMAN; S20A2_HUMAN; SC6A3_HUMAN; SEPT5_HUMAN SQSTM_HUMAN; SYNJ1_HUMAN; TAF1_HUMAN; TAU_HUMAN; TERA_HUMAN; TM230_HUMAN; TRPM7_HUMAN; VP13C_HUMAN; VPS35_HUMAN; WIPI4_HUMAN; XPR1_HUMAN.

  1. AIMP2_HUMAN

    AIMP2_HUMAN protein sequence analysis

    AIMP2_HUMAN polymorphic protein sequence analysis

    lung has 2 values

    lung I92V
    lung G209S


  2. AT132_HUMAN

    AT132_HUMAN protein sequence analysis

    AT132_HUMAN polymorphic protein sequence analysis

    patient has 1 value
    CLN12 has 1 value
    KRS has 4 values

    KRS F182L
    KRS G504R
    patient G533R
    CLN12 M854R
    KRS G877R
    KRS L1059R


  3. ATX2_HUMAN

    ATX2_HUMAN protein sequence analysis

    ATX2_HUMAN has no polymorphisms



  4. AUXI_HUMAN

    AUXI_HUMAN protein sequence analysis

    AUXI_HUMAN has no polymorphisms



  5. CDK5_HUMAN

    CDK5_HUMAN protein sequence analysis

    CDK5_HUMAN has no polymorphisms



  6. DCTN1_HUMAN

    DCTN1_HUMAN protein sequence analysis

    DCTN1_HUMAN polymorphic protein sequence analysis

    HMN7B has 1 value
    in has 1 value
    NORM has 1 value
    PERRYS has 7 values
    effect has 1 value
    ALS has 4 values

    PERRYS F52L
    HMN7B G59S
    PERRYS G71A
    PERRYS G71E
    PERRYS G71R
    PERRYS T72P
    PERRYS Q74P
    PERRYS Y78C
    NORM A163P
    effect I196V
    ALS M571T
    in Y670F
    ALS R785W
    ALS R1101K
    ALS T1249I


  7. DDIT4_HUMAN

    DDIT4_HUMAN protein sequence analysis

    DDIT4_HUMAN has no polymorphisms



  8. DPOG2_HUMAN

    DPOG2_HUMAN protein sequence analysis

    DPOG2_HUMAN polymorphic protein sequence analysis

    PEOA4 has 1 value
    is has 1 value

    is G416A
    PEOA4 G451E


  9. FGF20_HUMAN

    FGF20_HUMAN protein sequence analysis

    FGF20_HUMAN has no polymorphisms



  10. FXRD1_HUMAN

    FXRD1_HUMAN protein sequence analysis

    FXRD1_HUMAN polymorphic protein sequence analysis

    MT-C1D has 2 values

    MT-C1D R352W
    MT-C1D N430S


  11. IF4G1_HUMAN

    IF4G1_HUMAN protein sequence analysis

    IF4G1_HUMAN polymorphic protein sequence analysis

    colorectal has 1 value
    PARK18 has 2 values
    in has 3 values

    PARK18 A502V
    in G686C
    colorectal P696L
    in S1164R
    in R1197W
    PARK18 R1205H


  12. KLK6_HUMAN

    KLK6_HUMAN protein sequence analysis

    KLK6_HUMAN has no polymorphisms



  13. LRRK2_HUMAN

    LRRK2_HUMAN protein sequence analysis

    LRRK2_HUMAN polymorphic protein sequence analysis

    be has 1 value
    in has 1 value
    not has 1 value
    an has 2 values
    PARK8 has 25 values
    with has 1 value
    PARK has 1 value

    PARK8 M712V
    PARK8 R793M
    PARK8 Q930R
    PARK8 R1067Q
    PARK8 S1096C
    PARK8 I1122V
    PARK8 S1228T
    in K1359I
    PARK8 I1371V
    PARK R1441C
    PARK8 R1441G
    PARK8 R1441H
    PARK8 R1514Q
    PARK8 P1542S
    an R1550Q
    PARK8 V1598E
    be R1628P
    PARK8 Y1699C
    an R1723P
    PARK8 R1728H
    PARK8 R1728L
    PARK8 M1869T
    not K1906M
    PARK8 R1941H
    PARK8 I2012T
    PARK8 G2019S
    PARK8 I2020T
    PARK8 T2141M
    PARK8 R2143H
    PARK8 T2356I
    with G2385R
    PARK8 L2466H


  14. MIMIT_HUMAN

    MIMIT_HUMAN protein sequence analysis

    MIMIT_HUMAN has no polymorphisms



  15. NDUA1_HUMAN

    NDUA1_HUMAN protein sequence analysis

    NDUA1_HUMAN polymorphic protein sequence analysis

    MT-C1D has 2 values
    colorectal has 1 value

    MT-C1D G8R
    MT-C1D R37S
    colorectal R53C


  16. NDUF4_HUMAN

    NDUF4_HUMAN protein sequence analysis

    NDUF4_HUMAN polymorphic protein sequence analysis

    MT-C1D has 1 value

    MT-C1D L65P


  17. PARK7_HUMAN

    PARK7_HUMAN protein sequence analysis

    PARK7_HUMAN polymorphic protein sequence analysis

    PARK7 has 5 values
    disease-associated has 1 value

    PARK7 M26I
    disease-associated A39S
    PARK7 E64D
    PARK7 A104T
    PARK7 D149A
    PARK7 L166P


  18. PAWR_HUMAN

    PAWR_HUMAN protein sequence analysis

    PAWR_HUMAN has no polymorphisms



  19. PDE8B_HUMAN

    PDE8B_HUMAN protein sequence analysis

    PDE8B_HUMAN polymorphic protein sequence analysis

    PPNAD3 has 1 value

    PPNAD3 H305P


  20. PERQ2_HUMAN

    PERQ2_HUMAN protein sequence analysis

    PERQ2_HUMAN polymorphic protein sequence analysis

    be has 1 value
    PARK11 has 6 values

    be N56S
    PARK11 T112A
    PARK11 I278V
    PARK11 S335T
    PARK11 N457T
    PARK11 D606E
    PARK11 V1242I


  21. PGFRB_HUMAN

    PGFRB_HUMAN protein sequence analysis

    PGFRB_HUMAN polymorphic protein sequence analysis

    PENTT has 1 value
    gastric has 1 value
    IMF1 has 2 values
    KOGS has 1 value
    breast has 1 value
    IBGC4 has 3 values

    IMF1 R561C
    KOGS P584R
    gastric Y589H
    IBGC4 L658P
    IMF1 P660T
    PENTT V665A
    breast T882I
    IBGC4 R987W
    IBGC4 E1071V


  22. PIEZ1_HUMAN

    PIEZ1_HUMAN protein sequence analysis

    PIEZ1_HUMAN polymorphic protein sequence analysis

    DHS1 has 12 values
    LMPH3 has 4 values

    DHS1 G718S
    DHS1 G782S
    DHS1 R808Q
    LMPH3 L939M
    DHS1 S1117L
    DHS1 R1358P
    DHS1 A2003D
    DHS1 A2020T
    DHS1 A2020V
    DHS1 T2127M
    DHS1 M2225R
    LMPH3 P2430L
    LMPH3 R2456C
    DHS1 R2456H
    LMPH3 F2458L
    DHS1 R2488Q


  23. PINK1_HUMAN

    PINK1_HUMAN protein sequence analysis

    PINK1_HUMAN polymorphic protein sequence analysis

    PARK6 has 23 values
    glioblastoma has 1 value
    predispose has 5 values
    disease-associated has 1 value

    PARK6 C92F
    PARK6 C125G
    PARK6 Q126P
    PARK6 R147H
    PARK6 A168P
    PARK6 P196L
    glioblastoma P215L
    PARK6 A217D
    PARK6 E240K
    PARK6 L268V
    PARK6 H271Q
    PARK6 R279H
    PARK6 A280T
    PARK6 G309D
    PARK6 T313M
    PARK6 L347P
    PARK6 L369P
    PARK6 G386A
    PARK6 C388R
    disease-associated P399L
    PARK6 R407Q
    PARK6 G409V
    PARK6 E417G
    predispose Y431H
    predispose N451S
    PARK6 R464H
    predispose E476K
    PARK6 L489P
    predispose R501P
    predispose C575R


  24. PRKN2_HUMAN

    PRKN2_HUMAN protein sequence analysis

    PRKN2_HUMAN polymorphic protein sequence analysis

    patient has 2 values
    PARK2 has 28 values
    PARK has 2 values

    PARK2 V15M
    PARK2 R33Q
    PARK2 P37L
    PARK2 R42P
    PARK2 A46P
    PARK2 V56E
    PARK2 A82E
    PARK2 A92V
    PARK2 K161N
    PARK2 M192L
    PARK2 M192V
    PARK2 K211N
    PARK2 C212Y
    PARK2 T240M
    PARK2 T240R
    PARK C253Y
    PARK2 R256C
    PARK2 R275W
    PARK D280N
    PARK2 G284R
    PARK2 C289G
    patient Q311R
    PARK2 G328E
    PARK2 T351P
    patient A371T
    PARK2 R402C
    PARK2 T415N
    PARK2 C418R
    PARK2 G430D
    PARK2 C431F
    PARK2 P437L
    PARK2 C441R


  25. PRKRA_HUMAN

    PRKRA_HUMAN protein sequence analysis

    PRKRA_HUMAN polymorphic protein sequence analysis

    DYT16 has 1 value

    DYT16 P222L


  26. PSN1_HUMAN

    PSN1_HUMAN protein sequence analysis

    PSN1_HUMAN polymorphic protein sequence analysis

    gamma-secretase has 2 values
    disease-associated has 1 value
    CMD1U has 1 value
    NORM has 1 value
    in has 1 value
    frontotemporal has 1 value
    AD3 has 93 values

    AD3 R35Q
    AD3 A79V
    AD3 V82L
    AD3 I83T
    AD3 C92S
    AD3 V96F
    AD3 F105L
    frontotemporal L113P
    AD3 Y115C
    AD3 Y115H
    AD3 T116N
    AD3 P117L
    AD3 E120D
    AD3 E120K
    AD3 L134R
    AD3 N135D
    AD3 M139I
    AD3 M139K
    AD3 M139T
    AD3 M139V
    AD3 I143F
    AD3 I143T
    AD3 M146I
    AD3 M146L
    AD3 M146V
    AD3 T147I
    AD3 H163R
    AD3 H163Y
    AD3 W165C
    AD3 L166P
    AD3 S169L
    AD3 S169P
    AD3 L171P
    AD3 L173W
    AD3 L174M
    AD3 F177L
    AD3 F177S
    AD3 S178P
    AD3 G206A
    AD3 G206S
    AD3 G209E
    AD3 G209R
    AD3 G209V
    AD3 I213L
    AD3 I213T
    disease-associated H214Y
    AD3 L219P
    AD3 Q222R
    AD3 A231T
    AD3 A231V
    AD3 M233L
    AD3 M233T
    AD3 L235P
    AD3 A246E
    AD3 L250S
    AD3 A260V
    AD3 V261F
    AD3 L262F
    AD3 L262V
    AD3 C263R
    AD3 P264L
    AD3 G266S
    AD3 P267S
    AD3 P267T
    AD3 R269G
    AD3 R269H
    AD3 L271V
    AD3 T274R
    AD3 R278T
    AD3 E280A
    AD3 E280G
    AD3 L282R
    AD3 A285V
    AD3 L286V
    AD3 S289C
    in Y315C
    NORM E318G
    CMD1U D333G
    AD3 T354I
    AD3 R358Q
    AD3 S365Y
    AD3 G378E
    AD3 G384A
    AD3 S390I
    AD3 L392V
    AD3 G394V
    AD3 A396T
    AD3 N405S
    AD3 I408T
    AD3 A409T
    AD3 C410Y
    AD3 L418F
    AD3 A426P
    AD3 A431E
    gamma-secretase P433L
    AD3 L435F
    gamma-secretase L435R
    AD3 P436Q
    AD3 P436S
    AD3 I439V


  27. RNF11_HUMAN

    RNF11_HUMAN protein sequence analysis

    RNF11_HUMAN has no polymorphisms



  28. S20A2_HUMAN

    S20A2_HUMAN protein sequence analysis

    S20A2_HUMAN polymorphic protein sequence analysis

    IBGC1 has 19 values

    IBGC1 I11L
    IBGC1 D28N
    IBGC1 A51V
    IBGC1 L62P
    IBGC1 R71H
    IBGC1 T115M
    IBGC1 P184L
    IBGC1 N194S
    IBGC1 R382Q
    IBGC1 S434W
    IBGC1 G498R
    IBGC1 H502Q
    IBGC1 P568L
    IBGC1 G571S
    IBGC1 E575K
    IBGC1 T595M
    IBGC1 S601L
    IBGC1 S601W
    IBGC1 S637R


  29. SC6A3_HUMAN

    SC6A3_HUMAN protein sequence analysis

    SC6A3_HUMAN polymorphic protein sequence analysis

    breast has 2 values
    PKDYS has 2 values

    breast G121S
    PKDYS L368Q
    PKDYS P395L
    breast R544S


  30. SEPT5_HUMAN

    SEPT5_HUMAN protein sequence analysis

    SEPT5_HUMAN has no polymorphisms



  31. SQSTM_HUMAN

    SQSTM_HUMAN protein sequence analysis

    SQSTM_HUMAN polymorphic protein sequence analysis

    PDB3 has 7 values
    FTDALS3 has 20 values
    NORM has 1 value

    FTDALS3 A16V
    FTDALS3 A33V
    FTDALS3 D80E
    FTDALS3 V90M
    FTDALS3 R107W
    FTDALS3 D129N
    FTDALS3 V153I
    FTDALS3 R212C
    FTDALS3 G219V
    FTDALS3 S226P
    FTDALS3 P228L
    FTDALS3 P232T
    NORM K238E
    FTDALS3 D258N
    FTDALS3 S318P
    FTDALS3 R321C
    FTDALS3 D329G
    FTDALS3 P348L
    FTDALS3 S370P
    FTDALS3 A381V
    PDB3 P387L
    PDB3 P392L
    PDB3 S399P
    PDB3 M404T
    PDB3 M404V
    PDB3 G411S
    PDB3 G425R
    FTDALS3 T430P


  32. SYNJ1_HUMAN

    SYNJ1_HUMAN protein sequence analysis

    SYNJ1_HUMAN polymorphic protein sequence analysis

    PARK20 has 2 values

    PARK20 R219Q
    PARK20 S1383R


  33. TAF1_HUMAN

    TAF1_HUMAN protein sequence analysis

    TAF1_HUMAN polymorphic protein sequence analysis

    colorectal has 1 value
    MRXS33 has 7 values
    lung has 1 value
    metastatic has 1 value

    colorectal G453D
    MRXS33 P575S
    metastatic E651K
    lung M691I
    MRXS33 C786R
    MRXS33 D955H
    MRXS33 R1225W
    MRXS33 I1316T
    MRXS33 R1431H
    MRXS33 N1496H


  34. TAU_HUMAN

    TAU_HUMAN protein sequence analysis

    TAU_HUMAN polymorphic protein sequence analysis

    factor has 2 values
    FTD has 11 values
    PSNP1 has 2 values
    PIDB has 4 values
    FTD/Alzheimer has 1 value
    fatal has 1 value

    FTD R5H
    PSNP1 R5L
    factor D285N
    factor V289A
    PIDB K574T
    FTD L583V
    FTD G589V
    FTD N596K
    FTD N613H
    FTD P618L
    FTD P618S
    PSNP1 G620V
    FTD S622N
    FTD K634M
    PIDB S637F
    FTD V654M
    FTD E659V
    fatal S669L
    PIDB K686I
    PIDB G706R
    FTD/Alzheimer R723W


  35. TERA_HUMAN

    TERA_HUMAN protein sequence analysis

    TERA_HUMAN polymorphic protein sequence analysis

    IBMPFD1 has 7 values
    CMT2Y has 2 values
    ALS14 has 4 values
    NORM has 1 value

    IBMPFD1 R95G
    CMT2Y G97E
    IBMPFD1 I126F
    IBMPFD1 R155C
    ALS14 R155H
    IBMPFD1 R155P
    IBMPFD1 R155S
    ALS14 R159G
    IBMPFD1 R159H
    CMT2Y E185K
    ALS14 R191Q
    NORM L198W
    IBMPFD1 A232E
    ALS14 D592N


  36. TM230_HUMAN

    TM230_HUMAN protein sequence analysis

    TM230_HUMAN polymorphic protein sequence analysis

    PARK has 2 values

    PARK Y29C
    PARK R78L


  37. TRPM7_HUMAN

    TRPM7_HUMAN protein sequence analysis

    TRPM7_HUMAN polymorphic protein sequence analysis

    breast has 1 value
    gastric has 1 value
    an has 1 value
    channels has 1 value

    an S406C
    breast T720S
    gastric M830V
    channels T1482I


  38. VP13C_HUMAN

    VP13C_HUMAN protein sequence analysis

    VP13C_HUMAN polymorphic protein sequence analysis

    PARK23 has 1 value

    PARK23 G1389R


  39. VPS35_HUMAN

    VPS35_HUMAN protein sequence analysis

    VPS35_HUMAN polymorphic protein sequence analysis

    in has 3 values
    PARK17 has 1 value

    in I241M
    in P316S
    in R524W
    PARK17 D620N


  40. WIPI4_HUMAN

    WIPI4_HUMAN protein sequence analysis

    WIPI4_HUMAN has no polymorphisms



  41. XPR1_HUMAN

    XPR1_HUMAN protein sequence analysis

    XPR1_HUMAN polymorphic protein sequence analysis

    IBGC6 has 4 values

    IBGC6 S136N
    IBGC6 L140P
    IBGC6 L145P
    IBGC6 L218S