Disease Motifs
Investigating the Biomechanics of Disease
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Alzheimer's disease

This data set has been taken from the Swiss-Prot protein database which was downloaded from Uniprot on 17th & 18th of January 2017. There are a total of 96 proteins that seem to have some mention of Alzheimer's disease within the comments section of the protein datasheet.

  1. A4_HUMAN

    A4_HUMAN protein sequence analysis

    A4_HUMAN polymorphic protein sequence analysis

    patient has 1 value
    one has 1 value
    CAA-APP has 4 values
    AD1 has 13 values

    patient E665D
    AD1 D678N
    AD1 A692G
    AD1 E693G
    CAA-APP E693K
    CAA-APP E693Q
    CAA-APP D694N
    CAA-APP L705V
    AD1 A713T
    one A713V
    AD1 T714A
    AD1 T714I
    AD1 V715M
    AD1 I716V
    AD1 V717F
    AD1 V717G
    AD1 V717I
    AD1 V717L
    AD1 L723P


  2. AACT_HUMAN

    AACT_HUMAN protein sequence analysis

    AACT_HUMAN polymorphic protein sequence analysis

    with has 1 value
    Bochum-1 has 1 value
    Bonn-1 has 1 value
    NORM has 1 value

    Bochum-1 L78P
    NORM A167G
    Bonn-1 P252A
    with M401V


  3. AATC_HUMAN

    AATC_HUMAN protein sequence analysis

    AATC_HUMAN has no polymorphisms



  4. AATF_HUMAN

    AATF_HUMAN protein sequence analysis

    AATF_HUMAN has no polymorphisms



  5. ABCA7_HUMAN

    ABCA7_HUMAN protein sequence analysis

    ABCA7_HUMAN has no polymorphisms



  6. ADA10_HUMAN

    ADA10_HUMAN protein sequence analysis

    ADA10_HUMAN polymorphic protein sequence analysis

    RAK has 2 values
    cutaneous has 1 value
    AD18 has 2 values

    RAK P139S
    AD18 Q170H
    cutaneous H176Y
    AD18 R181G
    RAK C524Y


  7. APBB1_HUMAN

    APBB1_HUMAN protein sequence analysis

    APBB1_HUMAN has no polymorphisms



  8. APOE_HUMAN

    APOE_HUMAN protein sequence analysis

    APOE_HUMAN polymorphic protein sequence analysis

    E3 has 1 value
    HLPP3 has 9 values
    FH has 2 values
    NORM has 1 value
    form has 15 values
    LPG has 2 values

    form E21K
    HLPP3 E31K
    LPG R43C
    FH L46P
    form T60A
    NORM Q64H
    form Q99K
    form P102R
    form A117T
    form A124V
    HLPP3 C130R
    FH G145D
    form R152Q
    HLPP3 R154C
    HLPP3 R154S
    HLPP3 R160C
    HLPP3 R163C
    E3 R163H
    LPG R163P
    HLPP3 K164E
    HLPP3 K164Q
    form A170P
    HLPP3 R176C
    form R242Q
    form R246C
    form V254E
    form R269G
    form L270E
    form R292H
    form S314R


  9. ASA2B_HUMAN

    ASA2B_HUMAN protein sequence analysis

    ASA2B_HUMAN has no polymorphisms



  10. ATS4_HUMAN

    ATS4_HUMAN protein sequence analysis

    ATS4_HUMAN has no polymorphisms



  11. BACE1_HUMAN

    BACE1_HUMAN protein sequence analysis

    BACE1_HUMAN has no polymorphisms



  12. BACE2_HUMAN

    BACE2_HUMAN protein sequence analysis

    BACE2_HUMAN has no polymorphisms



  13. BHLH9_HUMAN

    BHLH9_HUMAN protein sequence analysis

    BHLH9_HUMAN has no polymorphisms



  14. BPTF_HUMAN

    BPTF_HUMAN protein sequence analysis

    BPTF_HUMAN has no polymorphisms



  15. CAHM1_HUMAN

    CAHM1_HUMAN protein sequence analysis

    CAHM1_HUMAN has no polymorphisms



  16. CASP4_HUMAN

    CASP4_HUMAN protein sequence analysis

    CASP4_HUMAN has no polymorphisms



  17. CATD_HUMAN

    CATD_HUMAN protein sequence analysis

    CATD_HUMAN polymorphic protein sequence analysis

    CLN10 has 2 values
    with has 1 value

    with A58V
    CLN10 F229I
    CLN10 W383C


  18. CD5R1_HUMAN

    CD5R1_HUMAN protein sequence analysis

    CD5R1_HUMAN has no polymorphisms



  19. CDK5_HUMAN

    CDK5_HUMAN protein sequence analysis

    CDK5_HUMAN has no polymorphisms



  20. COL12_HUMAN

    COL12_HUMAN protein sequence analysis

    COL12_HUMAN has no polymorphisms



  21. COPA1_HUMAN

    COPA1_HUMAN protein sequence analysis

    COPA1_HUMAN polymorphic protein sequence analysis

    CFEOM5 has 1 value

    CFEOM5 G382R


  22. CSEN_HUMAN

    CSEN_HUMAN protein sequence analysis

    CSEN_HUMAN polymorphic protein sequence analysis

    breast has 2 values

    breast A170S
    breast D179Y


  23. CSTN1_HUMAN

    CSTN1_HUMAN protein sequence analysis

    CSTN1_HUMAN has no polymorphisms



  24. CT203_HUMAN

    CT203_HUMAN protein sequence analysis

    CT203_HUMAN has no polymorphisms



  25. DHC24_HUMAN

    DHC24_HUMAN protein sequence analysis

    DHC24_HUMAN polymorphic protein sequence analysis

    DESMOS has 4 values

    DESMOS E191K
    DESMOS N294T
    DESMOS K306N
    DESMOS Y471S


  26. DKK1_HUMAN

    DKK1_HUMAN protein sequence analysis

    DKK1_HUMAN has no polymorphisms



  27. DKK2_HUMAN

    DKK2_HUMAN protein sequence analysis

    DKK2_HUMAN has no polymorphisms



  28. DKK3_HUMAN

    DKK3_HUMAN protein sequence analysis

    DKK3_HUMAN has no polymorphisms



  29. DKK4_HUMAN

    DKK4_HUMAN protein sequence analysis

    DKK4_HUMAN has no polymorphisms



  30. DNM1L_HUMAN

    DNM1L_HUMAN protein sequence analysis

    DNM1L_HUMAN polymorphic protein sequence analysis

    EMPF1 has 4 values

    EMPF1 G362D
    EMPF1 G362S
    EMPF1 A395D
    EMPF1 R403C


  31. DOCK3_HUMAN

    DOCK3_HUMAN protein sequence analysis

    DOCK3_HUMAN has no polymorphisms



  32. DPYL2_HUMAN

    DPYL2_HUMAN protein sequence analysis

    DPYL2_HUMAN polymorphic protein sequence analysis

    colorectal has 1 value

    colorectal R481C


  33. E2AK2_HUMAN

    E2AK2_HUMAN protein sequence analysis

    E2AK2_HUMAN polymorphic protein sequence analysis

    lung has 1 value

    lung L439V


  34. ECE2_HUMAN

    ECE2_HUMAN protein sequence analysis

    ECE2_HUMAN has no polymorphisms



  35. F168B_HUMAN

    F168B_HUMAN protein sequence analysis

    F168B_HUMAN has no polymorphisms



  36. FLNB_HUMAN

    FLNB_HUMAN protein sequence analysis

    FLNB_HUMAN polymorphic protein sequence analysis

    breast has 4 values
    BOOMD has 2 values
    LRS has 12 values
    AO3 has 1 value
    AO1 has 3 values

    LRS F161C
    LRS G168S
    BOOMD L171R
    AO1 A173V
    AO1 S188P
    AO1 M202V
    LRS E227K
    LRS L234V
    BOOMD S235P
    LRS G361S
    LRS G363E
    breast R566Q
    breast N663K
    breast T703K
    AO3 G751R
    LRS L1431R
    breast A1534G
    LRS G1586R
    LRS V1592D
    LRS P1603L
    LRS G1691S
    LRS G1834R


  37. FOLH1_HUMAN

    FOLH1_HUMAN protein sequence analysis

    FOLH1_HUMAN polymorphic protein sequence analysis

    colorectal has 1 value
    be has 1 value

    colorectal A23T
    be H475Y


  38. G3P_HUMAN

    G3P_HUMAN protein sequence analysis

    G3P_HUMAN has no polymorphisms



  39. GDNF_HUMAN

    GDNF_HUMAN protein sequence analysis

    GDNF_HUMAN polymorphic protein sequence analysis

    HSCR3 has 4 values
    HSCR3, has 1 value

    HSCR3 P21S
    HSCR3, R93W
    HSCR3 D150N
    HSCR3 T154S
    HSCR3 I211M


  40. GPC1_HUMAN

    GPC1_HUMAN protein sequence analysis

    GPC1_HUMAN polymorphic protein sequence analysis

    breast has 1 value

    breast A337D


  41. GPR3_HUMAN

    GPR3_HUMAN protein sequence analysis

    GPR3_HUMAN has no polymorphisms



  42. GSAP_HUMAN

    GSAP_HUMAN protein sequence analysis

    GSAP_HUMAN has no polymorphisms



  43. GSK3A_HUMAN

    GSK3A_HUMAN protein sequence analysis

    GSK3A_HUMAN has no polymorphisms



  44. GSK3B_HUMAN

    GSK3B_HUMAN protein sequence analysis

    GSK3B_HUMAN has no polymorphisms



  45. HCD2_HUMAN

    HCD2_HUMAN protein sequence analysis

    HCD2_HUMAN polymorphic protein sequence analysis

    MHBD has 3 values

    MHBD L122V
    MHBD R130C
    MHBD N247S


  46. HERP1_HUMAN

    HERP1_HUMAN protein sequence analysis

    HERP1_HUMAN has no polymorphisms



  47. HMGB1_HUMAN

    HMGB1_HUMAN protein sequence analysis

    HMGB1_HUMAN polymorphic protein sequence analysis

    gastric-carcinoma has 3 values

    gastric-carcinoma G11R
    gastric-carcinoma A149E
    gastric-carcinoma D190G


  48. HRH2_HUMAN

    HRH2_HUMAN protein sequence analysis

    HRH2_HUMAN polymorphic protein sequence analysis

    NORM has 3 values

    NORM N217D
    NORM K231R
    NORM V268M


  49. HUNIN_HUMAN

    HUNIN_HUMAN protein sequence analysis

    HUNIN_HUMAN has no polymorphisms



  50. KC1D_HUMAN

    KC1D_HUMAN protein sequence analysis

    KC1D_HUMAN polymorphic protein sequence analysis

    FASPS2 has 2 values
    breast has 1 value

    FASPS2 T44A
    FASPS2 H46R
    breast S97C


  51. KLK8_HUMAN

    KLK8_HUMAN protein sequence analysis

    KLK8_HUMAN has no polymorphisms



  52. LRP8_HUMAN

    LRP8_HUMAN protein sequence analysis

    LRP8_HUMAN polymorphic protein sequence analysis

    with has 1 value

    with R952Q


  53. MARK1_HUMAN

    MARK1_HUMAN protein sequence analysis

    MARK1_HUMAN polymorphic protein sequence analysis

    gastric has 1 value
    an has 1 value

    gastric Y233C
    an N355T


  54. MAZ_HUMAN

    MAZ_HUMAN protein sequence analysis

    MAZ_HUMAN has no polymorphisms



  55. MT3_HUMAN

    MT3_HUMAN protein sequence analysis

    MT3_HUMAN has no polymorphisms



  56. NDRG2_HUMAN

    NDRG2_HUMAN protein sequence analysis

    NDRG2_HUMAN has no polymorphisms



  57. NEUG_HUMAN

    NEUG_HUMAN protein sequence analysis

    NEUG_HUMAN has no polymorphisms



  58. NU1M_HUMAN

    NU1M_HUMAN protein sequence analysis

    NU1M_HUMAN polymorphic protein sequence analysis

    MELAS has 1 value
    contribute has 1 value
    MT-C1D has 1 value
    AD-MT has 1 value
    LHON has 4 values
    patient has 1 value

    contribute A4T
    patient Y30C
    LHON Y30H
    MELAS M31T
    AD-MT M31V
    LHON A52T
    MT-C1D E214K
    LHON L285P
    LHON Y304H


  59. NU2M_HUMAN

    NU2M_HUMAN protein sequence analysis

    NU2M_HUMAN polymorphic protein sequence analysis

    AD-MT has 1 value
    LHON has 2 values

    LHON N150D
    LHON G259S
    AD-MT A331S


  60. OGT1_HUMAN

    OGT1_HUMAN protein sequence analysis

    OGT1_HUMAN polymorphic protein sequence analysis

    in has 1 value
    disease-associated has 1 value

    disease-associated A319T
    in L538P


  61. OLR1_HUMAN

    OLR1_HUMAN protein sequence analysis

    OLR1_HUMAN polymorphic protein sequence analysis

    polymorphism has 1 value

    polymorphism K167N


  62. P33MX_HUMAN

    P33MX_HUMAN protein sequence analysis

    P33MX_HUMAN has no polymorphisms



  63. PAWR_HUMAN

    PAWR_HUMAN protein sequence analysis

    PAWR_HUMAN has no polymorphisms



  64. PCSK1_HUMAN

    PCSK1_HUMAN protein sequence analysis

    PCSK1_HUMAN has no polymorphisms



  65. PGH1_HUMAN

    PGH1_HUMAN protein sequence analysis

    PGH1_HUMAN has no polymorphisms



  66. PGH2_HUMAN

    PGH2_HUMAN protein sequence analysis

    PGH2_HUMAN has no polymorphisms



  67. PIEZ1_HUMAN

    PIEZ1_HUMAN protein sequence analysis

    PIEZ1_HUMAN polymorphic protein sequence analysis

    DHS1 has 12 values
    LMPH3 has 4 values

    DHS1 G718S
    DHS1 G782S
    DHS1 R808Q
    LMPH3 L939M
    DHS1 S1117L
    DHS1 R1358P
    DHS1 A2003D
    DHS1 A2020T
    DHS1 A2020V
    DHS1 T2127M
    DHS1 M2225R
    LMPH3 P2430L
    LMPH3 R2456C
    DHS1 R2456H
    LMPH3 F2458L
    DHS1 R2488Q


  68. PLD3_HUMAN

    PLD3_HUMAN protein sequence analysis

    PLD3_HUMAN polymorphic protein sequence analysis

    in has 1 value

    in V232M


  69. PREP_HUMAN

    PREP_HUMAN protein sequence analysis

    PREP_HUMAN has no polymorphisms



  70. PSA_HUMAN

    PSA_HUMAN protein sequence analysis

    PSA_HUMAN has no polymorphisms



  71. PSN1_HUMAN

    PSN1_HUMAN protein sequence analysis

    PSN1_HUMAN polymorphic protein sequence analysis

    NORM has 1 value
    frontotemporal has 1 value
    disease-associated has 1 value
    gamma-secretase has 2 values
    in has 1 value
    CMD1U has 1 value
    AD3 has 93 values

    AD3 R35Q
    AD3 A79V
    AD3 V82L
    AD3 I83T
    AD3 C92S
    AD3 V96F
    AD3 F105L
    frontotemporal L113P
    AD3 Y115C
    AD3 Y115H
    AD3 T116N
    AD3 P117L
    AD3 E120D
    AD3 E120K
    AD3 L134R
    AD3 N135D
    AD3 M139I
    AD3 M139K
    AD3 M139T
    AD3 M139V
    AD3 I143F
    AD3 I143T
    AD3 M146I
    AD3 M146L
    AD3 M146V
    AD3 T147I
    AD3 H163R
    AD3 H163Y
    AD3 W165C
    AD3 L166P
    AD3 S169L
    AD3 S169P
    AD3 L171P
    AD3 L173W
    AD3 L174M
    AD3 F177L
    AD3 F177S
    AD3 S178P
    AD3 G206A
    AD3 G206S
    AD3 G209E
    AD3 G209R
    AD3 G209V
    AD3 I213L
    AD3 I213T
    disease-associated H214Y
    AD3 L219P
    AD3 Q222R
    AD3 A231T
    AD3 A231V
    AD3 M233L
    AD3 M233T
    AD3 L235P
    AD3 A246E
    AD3 L250S
    AD3 A260V
    AD3 V261F
    AD3 L262F
    AD3 L262V
    AD3 C263R
    AD3 P264L
    AD3 G266S
    AD3 P267S
    AD3 P267T
    AD3 R269G
    AD3 R269H
    AD3 L271V
    AD3 T274R
    AD3 R278T
    AD3 E280A
    AD3 E280G
    AD3 L282R
    AD3 A285V
    AD3 L286V
    AD3 S289C
    in Y315C
    NORM E318G
    CMD1U D333G
    AD3 T354I
    AD3 R358Q
    AD3 S365Y
    AD3 G378E
    AD3 G384A
    AD3 S390I
    AD3 L392V
    AD3 G394V
    AD3 A396T
    AD3 N405S
    AD3 I408T
    AD3 A409T
    AD3 C410Y
    AD3 L418F
    AD3 A426P
    AD3 A431E
    gamma-secretase P433L
    AD3 L435F
    gamma-secretase L435R
    AD3 P436Q
    AD3 P436S
    AD3 I439V


  72. PSN2_HUMAN

    PSN2_HUMAN protein sequence analysis

    PSN2_HUMAN polymorphic protein sequence analysis

    AD4 has 7 values
    CMD1V has 1 value

    AD4 R62H
    AD4 R71W
    AD4 T122P
    CMD1V S130L
    AD4 N141I
    AD4 V148I
    AD4 M239I
    AD4 M239V


  73. RBG1L_HUMAN

    RBG1L_HUMAN protein sequence analysis

    RBG1L_HUMAN has no polymorphisms



  74. REG1A_HUMAN

    REG1A_HUMAN protein sequence analysis

    REG1A_HUMAN has no polymorphisms



  75. RGPS2_HUMAN

    RGPS2_HUMAN protein sequence analysis

    RGPS2_HUMAN has no polymorphisms



  76. RN146_HUMAN

    RN146_HUMAN protein sequence analysis

    RN146_HUMAN has no polymorphisms



  77. RN182_HUMAN

    RN182_HUMAN protein sequence analysis

    RN182_HUMAN polymorphic protein sequence analysis

    colorectal has 2 values

    colorectal V43A
    colorectal P58L


  78. SDIM1_HUMAN

    SDIM1_HUMAN protein sequence analysis

    SDIM1_HUMAN has no polymorphisms



  79. SORL_HUMAN

    SORL_HUMAN protein sequence analysis

    SORL_HUMAN polymorphic protein sequence analysis

    colorectal has 1 value
    breast has 2 values
    AD has 5 values

    breast L120S
    AD Y141C
    AD G511R
    AD N924S
    AD N1358S
    breast M1581L
    AD G1681D
    colorectal L1972V


  80. SPN90_HUMAN

    SPN90_HUMAN protein sequence analysis

    SPN90_HUMAN has no polymorphisms



  81. SQSTM_HUMAN

    SQSTM_HUMAN protein sequence analysis

    SQSTM_HUMAN polymorphic protein sequence analysis

    PDB3 has 7 values
    NORM has 1 value
    FTDALS3 has 20 values

    FTDALS3 A16V
    FTDALS3 A33V
    FTDALS3 D80E
    FTDALS3 V90M
    FTDALS3 R107W
    FTDALS3 D129N
    FTDALS3 V153I
    FTDALS3 R212C
    FTDALS3 G219V
    FTDALS3 S226P
    FTDALS3 P228L
    FTDALS3 P232T
    NORM K238E
    FTDALS3 D258N
    FTDALS3 S318P
    FTDALS3 R321C
    FTDALS3 D329G
    FTDALS3 P348L
    FTDALS3 S370P
    FTDALS3 A381V
    PDB3 P387L
    PDB3 P392L
    PDB3 S399P
    PDB3 M404T
    PDB3 M404V
    PDB3 G411S
    PDB3 G425R
    FTDALS3 T430P


  82. SR1IP_HUMAN

    SR1IP_HUMAN protein sequence analysis

    SR1IP_HUMAN has no polymorphisms



  83. SYUA_HUMAN

    SYUA_HUMAN protein sequence analysis

    SYUA_HUMAN polymorphic protein sequence analysis

    PARK1 has 4 values

    PARK1 A30P
    PARK1 E46K
    PARK1 H50Q
    PARK1 A53T


  84. SYUB_HUMAN

    SYUB_HUMAN protein sequence analysis

    SYUB_HUMAN has no polymorphisms



  85. TAU_HUMAN

    TAU_HUMAN protein sequence analysis

    TAU_HUMAN polymorphic protein sequence analysis

    fatal has 1 value
    FTD/Alzheimer has 1 value
    FTD has 11 values
    PSNP1 has 2 values
    factor has 2 values
    PIDB has 4 values

    FTD R5H
    PSNP1 R5L
    factor D285N
    factor V289A
    PIDB K574T
    FTD L583V
    FTD G589V
    FTD N596K
    FTD N613H
    FTD P618L
    FTD P618S
    PSNP1 G620V
    FTD S622N
    FTD K634M
    PIDB S637F
    FTD V654M
    FTD E659V
    fatal S669L
    PIDB K686I
    PIDB G706R
    FTD/Alzheimer R723W


  86. TEFF2_HUMAN

    TEFF2_HUMAN protein sequence analysis

    TEFF2_HUMAN has no polymorphisms



  87. TM119_HUMAN

    TM119_HUMAN protein sequence analysis

    TM119_HUMAN has no polymorphisms



  88. TNR21_HUMAN

    TNR21_HUMAN protein sequence analysis

    TNR21_HUMAN has no polymorphisms



  89. TSH1_HUMAN

    TSH1_HUMAN protein sequence analysis

    TSH1_HUMAN has no polymorphisms



  90. TSH2_HUMAN

    TSH2_HUMAN protein sequence analysis

    TSH2_HUMAN has no polymorphisms



  91. TSH3_HUMAN

    TSH3_HUMAN protein sequence analysis

    TSH3_HUMAN has no polymorphisms



  92. UBB_HUMAN

    UBB_HUMAN protein sequence analysis

    UBB_HUMAN has no polymorphisms



  93. UBXN4_HUMAN

    UBXN4_HUMAN protein sequence analysis

    UBXN4_HUMAN has no polymorphisms



  94. UCHL1_HUMAN

    UCHL1_HUMAN protein sequence analysis

    UCHL1_HUMAN polymorphic protein sequence analysis

    NDGOA has 1 value
    NORM has 1 value
    PARK5 has 1 value

    NDGOA E7A
    NORM S18Y
    PARK5 I93M


  95. VISL1_HUMAN

    VISL1_HUMAN protein sequence analysis

    VISL1_HUMAN has no polymorphisms



  96. VP26A_HUMAN

    VP26A_HUMAN protein sequence analysis

    VP26A_HUMAN has no polymorphisms